(4-fluorophenyl)(2-(piperazin-1-yl)pyrimidin- 5-yl)methanone

IUPAC Name: (4-fluorophenyl)(2-(piperazin-1-yl)pyrimidin- 5-yl)methanone

Synonyms: (4-fluorophenyl)(2-(piperazin-1-yl)pyrimidin-5-yl)methanone;Methanone, (4-fluorophenyl)[2-(1-piperazinyl)-5-pyrimidinyl]-, 

Catalog NO.:
CAS NO.: 1703794-75-5
Brand: Daisa Biopharma
Category: Heterocyles
Tag: Avapritinib Intermediate, Hererocycles, Avapritinib, 

Molecular Formula: C15H15N4FO

Molecular Weight: 286.304
Pack Size Available: 25 g, 100 g, 1.0 kg
Place of Origin: India

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cGMP Capacity

kg to MT scale
GMP batches production
Over 20 years of experience

HPAPI production with OEL < 1 μg/m³
Cleanroom Class 100 to Class 100,000
Special type of reactions in cGMP workshop

Cleaning level: Class A B C
cGMP synthesis workshop

Product Description

  • Key intermediate for drug Avapritinib synthesis.
  • As an intermediate in the synthesis of pharmaceutical compounds.

 

 

Appearance: Liquid

HPLC purity: ≥98% a/a

NMR: Confirm the structure

 

 

SMILESC1CN(CCN1)C2=NC=C(C=N2)C(=O)C3=CC=C(C=C3)F
InChIKeyMEKXTXCAIYGVMF-UHFFFAOYSA-N
InChI: InChI=1S/C15H15FN4O/c16-13-3-1-11(2-4-13)14(21)12-9-18-15(19-10-12)20-7-5-17-6-8-20/h1-4,9-10,17H,5-8H2

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Our medicinal chemistry division drives early-stage drug discovery through the design and synthesis of novel chemical entities, SAR exploration, and creation of natural-product-inspired molecular libraries.

We develop safe, robust, and scalable synthetic routes for APIs and intermediates. Our expertise covers QbD-driven development, impurity profiling, polymorph optimization, and complete CMC/DMF support.

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